Amyloidosis is an extracellular deposition disease, with primary amyloidosis being rare. In addition, gastrointestinal presentation is unusual, rarely the form of onset of the disease.
We describe a case of systemic amyloidosis in which the diagnosis is reach due to the gastrointestinal involvement with digestive clinical debut.
As conclusion, we describe this disease to take it into account as differential diagnosis of certain digestive symptomatology, even if it is non-specific.
Keywords: amyloidosis, gastrointestinal, systemic amyloidosis.